Flixotide is used in cases of chronic asthma and severe asthma. Salmeterol is added to fluticasone. This combination is used in the continuous treatment of asthma that has not been completely controlled using inhaled corticosteroids, or in cases of stabilization using salmeterol and fluticasone.
Flixotide is also used in cases of seasonal and annual allergies and can be used in the treatment of sinusitis and is also used in cases of chronic obstructive pulmonary disease.