Vendofenac eye drops are a topical nonsteroidal anti-inflammatory drug (NSAID) specifically designed to manage the pain and inflammation that often occur after cataract surgery, a common surgical procedure to remove a cloudy lens and replace it with an artificial lens. These drops contain nepafenac as their active ingredient, which effectively reduces the production of chemicals in the eye that cause pain, swelling, and inflammation, contributing to a more comfortable and smooth recovery for patients after surgery.
Active Ingredients in Vendofenac Eye Drops
Vindofenac eye drops contain the following active ingredients:
Nepafenac: Present in a 0.1% concentration in the ophthalmic formulation. Nepafenac is a prodrug that is converted within the eye to its active form, amfenac, by enzymes present in the eye tissue. Amfenac has a potent ability to inhibit cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the production of prostaglandins, the main substances that cause pain and inflammation. This local conversion helps achieve a targeted therapeutic effect within the eye while reducing systemic exposure to the drug.
Available Concentrations
Vendofenac eye drops are available in a 0.1% concentration of nepafenac. This concentration is the most common and effective for use after cataract surgery. Available pack sizes may vary.
Indications for Use of Vendofenac Eye Drops
The primary use of Vendofenac eye drops is to:
Treat inflammation and eye pain after cataract surgery: It helps reduce pain, swelling, redness, and light sensitivity that may occur after surgery, promoting healing and improving vision.
Drug Interactions for Vendofenac Eye Drops
Patients should inform their ophthalmologist of all other ophthalmic or oral medications they are using, including eye drops, ointments, and nutritional supplements. In particular, caution should be exercised when using Vindofenac eye drops in conjunction with:
Topical ophthalmic corticosteroids: Concomitant use may increase the risk of corneal problems or delayed wound healing.
Other NSAIDs (ophthalmic or oral): Concomitant use may increase the risk of side effects.