Futavildix tablets are an innovative oral combination medicine used to treat type 2 diabetes in adults. This medicine combines two active ingredients with different yet complementary mechanisms of action to help achieve and effectively control blood sugar levels. Type 2 diabetes is a chronic condition characterized by high blood glucose (sugar) levels resulting from tissue resistance to insulin or insufficient insulin production by the pancreas. Futavildix tablets provide a dual-drug treatment approach that targets multiple aspects of this complex problem.
The active ingredients in Futavildix tablets
Each Futavildix tablet contains a combination of two active ingredients that work synergistically to improve blood sugar control:
Vildagliptin: It belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. Vildagliptin works by blocking the action of the DPP-4 enzyme, which breaks down incretin hormones in the body. Incretin hormones (such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)) increase insulin secretion from the pancreas in response to food intake and reduce glucagon secretion (a blood sugar-raising hormone). By inhibiting DPP-4, vildagliptin increases levels of these hormones, leading to improved insulin secretion and reduced glucagon secretion, thus lowering blood sugar levels after and between meals.
Metformin hydrochloride: This is a biguanide and a cornerstone of type 2 diabetes treatment. Metformin works primarily by reducing glucose production in the liver and increasing tissue sensitivity to insulin, allowing cells to absorb and utilize glucose more effectively. In addition, metformin may help reduce glucose absorption from the intestine. Metformin does not directly stimulate insulin secretion, so the risk of low blood sugar (hypoglycemia) is relatively low when used alone.
Available Strengths
Futavildix tablets are available in various strengths that combine specific doses of vildagliptin and metformin hydrochloride to provide flexible treatment options and meet different patient needs. Common strengths include:
50 mg vildagliptin / 500 mg metformin hydrochloride
50 mg vildagliptin / 850 mg metformin hydrochloride
50 mg vildagliptin / 1000 mg metformin hydrochloride
The doctor determines the appropriate combination and dose based on the patient's blood sugar level, response to treatment, other medications they may be taking, and their general health.
Indications for Use of Futavildix Tablets
Futavildix tablets are used to treat type 2 diabetes in adults in the following cases:
When diet and exercise alone are not sufficient to control blood sugar levels adequately.
As initial treatment in some patients with type 2 diabetes who are likely to benefit from combination therapy.
In addition to other diabetes medications, such as insulin or sulfonylureas, to improve blood sugar control.