Quadel tablets are a powerful and versatile oral medication containing the active ingredient quetiapine at a strength of 25 mg per tablet. Quetiapine belongs to a class of medications known as atypical antipsychotics, which have a unique mechanism of action that affects a variety of neurotransmitters in the brain, making it effective in treating a wide range of psychiatric disorders. Quadel is effectively used to manage the symptoms of schizophrenia, including hallucinations, delusions, disorganized thinking, and negative symptoms; to control bipolar disorder, where it helps treat and prevent episodes of mania and depression; to be used as an add-on treatment for major depressive disorder when the response to antidepressants alone is inadequate; and to be used in low doses to treat insomnia associated with bipolar disorder. Quetiapine's ability to affect dopamine, serotonin, histamine, and adrenaline makes it a valuable treatment option for a variety of psychiatric conditions.
The active ingredient in Quadel tablets
Quadel tablets contain the following active ingredient, which is the basis of its therapeutic effect in the management of various psychiatric disorders:
Quetiapine: A chemical compound belonging to the atypical antipsychotic class. It has a complex mechanism of action involving effects on multiple receptors in the brain. Quetiapine works primarily by blocking dopamine receptors (especially D2) and serotonin receptors (especially 5-HT2A), contributing to the relief of psychotic symptoms. Additionally, quetiapine has an affinity for H1 histamine receptors and alpha-1 and alpha-2 adrenergic receptors, which may explain some of its side effects and other uses, such as treating insomnia. The balance of its effects on these different neurotransmitters makes it effective in treating a variety of psychiatric disorders while minimizing the risk of extrapyramidal side effects (EPS) often associated with traditional antipsychotics.
Available Strengths
Quadel tablets are available in a wide range of different quetiapine strengths to provide flexibility in dose adjustment and meet individual patient treatment needs based on the type and severity of the disorder and their response to treatment:
25 mg: This strength is often used as a low starting dose to initiate treatment and assess patient tolerance, or as a therapeutic dose for insomnia associated with bipolar disorder.
50 mg, 100 mg, 200 mg, and 300 mg: These strengths are commonly used in the treatment of schizophrenia, bipolar disorder, and major depressive disorder, where the dose is gradually adjusted to achieve the optimal therapeutic dose.
Higher strengths (such as 400 mg or more) may be necessary for some patients with severe symptoms or partial response to lower doses. The initial and therapeutic doses are determined and gradually adjusted by a specialist psychiatrist based on a careful assessment of the patient's clinical condition, severity of symptoms, response to treatment, and tolerance to potential side effects. The doctor's instructions regarding the dosage and medication schedule must be strictly adhered to and should not be changed or discontinued on your own. Quadel is usually taken once or twice a day, depending on the condition being treated and the doctor's recommendations.
Indications for Use of Quadel Tablets
Quadel tablets are primarily used to treat a variety of psychiatric disorders that affect mood, thinking, and behavior, including:
Schizophrenia: Helps relieve positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and loss of motivation), and thought disorders.
Manic and Depressive Episodes Associated with Bipolar Disorder: Used to treat acute and moderate manic episodes. It can also be used as a preventative treatment to prevent recurrence of manic and depressive episodes. It is also used to treat depressive episodes associated with bipolar disorder. Major depressive disorder: It is used as an add-on treatment with other antidepressants in patients who have not responded adequately to antidepressant treatment alone.
Insomnia associated with bipolar disorder: It can be used in low doses to improve sleep in patients with insomnia as part of bipolar disorder.