Comparison of the difference between Anafranil and Tofranil tablets for depression treatment

23 April 2025

Comparison of the difference between Anafranil and Tofranil tablets for depression treatment

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    • Anafranil and Tofranil are both used to treat depression, and both belong to the tricyclic antidepressant class (TCAs). However, they differ in the active ingredient they contain, leading to differences in effectiveness and potential side effects, particularly regarding their effects on different neurotransmitters.

      Anafranil Tablets Ingredients

      Anafranil tablets contain the active ingredient clomipramine. Clomipramine is a tricyclic antidepressant with a strong effect on the serotonin system. Although it also affects norepinephrine, its effect on serotonin reuptake is much stronger than that of many other tricyclic antidepressants. Clomipramine is particularly used to treat obsessive-compulsive disorder (OCD).

      Tofranil Tablets Ingredients

      Tofranil tablets contain the active ingredient imipramine. Imipramine is also a tricyclic antidepressant, but it tends to have a more balanced effect on serotonin and norepinephrine reuptake. Imipramine is primarily used to treat depression and may also be used for other conditions, such as bedwetting in children (under close medical supervision).

      About Anafranil Tablets

      Drug Class: Antidepressants

      Drug Classification: Tricyclic antidepressants (TCAs)

      Pharmaceutical Form: Coated Tablets

      Pharmaceutical Family: Central Nervous System Drugs

      Active Ingredient: Clomipramine

      About Tofranil Tablets

      Drug Class: Antidepressants

      Drug Classification: Tricyclic antidepressants (TCAs)

      Pharmaceutical Form: Coated Tablets

      Pharmaceutical Family: Central Nervous System Drugs

      Active Ingredient: Imipramine


      you should ask your doctor before taking this medicine

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