Cetafen is used to treat and relieve pain and reduce fever. Cetafen is used in conditions such as headache, joint pain, menstrual pain, and muscle pain, in addition to reducing fever associated with colds and flu. Cetafen is used as an analgesic and anti-inflammatory in the treatment of urinary tract infections, acute otitis media, acute exacerbation of chronic bronchitis in adults, and pneumonia.