Lamprene capsules are used to treat leprosy including cases resistant to dapsone as well as cases complicated by erythema nodosum associated with leprosy. To avoid the development of bacterial resistance to clofazimine, it should be used in conjunction with other drugs for the treatment of leprosy.
Lamprene works by inhibiting the reproduction of Mycobacterium tuberculosis bacteria as it selectively binds to its DNA, which hinders the process of bacterial DNA synthesis.