Medicine Description
Mechanism of Action of Ginkgo Biloba The mechanism of action of ginkgo is believed to be produced by its functions as a neuroprotective agent, an antioxidant, a free-radical scavenger, a membrane stabilizer, and an inhibitor of platelet-activating factor via the terpene ginkgolide B.Other pharmacologic effects include the following: endothelium relaxation mediated by inhibition of 3',5'-cyclic GMP (guanosine monophosphate) phosphodiesterase- inhibition of age-related loss of muscarinergic cholinoceptors and ?-adrenoceptors- and stimulation of choline uptake in the hippocampus.Ginkgo extract also has been shown to inhibit beta-amyloid deposition. Indications for Ginkgo Biloba 1.Dementia 2.Cerebrovascular and peripheral activator