Zemadermin

  • Scientific Name: Hydrocortisone 1% acetate +Urea 10% +Lactic acid 5%
  • Dosage: 1%
  • Type: Cream
EGP

Price: 7.50 EGP

31/12/2025

    Medicine Description

    About Hydrocortisone Systemic synthetic glucocorticoid, anti-inflammatory Mechanism of Action of Hydrocortisone The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts both glucocorticoid and mineralocorticoid actions. The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages,
    you should ask your doctor before taking this medicine