Both PK-Merz and Stalipark are used to treat Parkinson's disease, a progressive neurological disorder that affects movement. However, they contain different active ingredients that belong to different pharmacological classes and work by different mechanisms to relieve the symptoms of this disease. Understanding these differences helps determine the most appropriate medication for each patient.
PK-Merz Tablets Ingredients
PK-Merz Tablets contain the active ingredient amantadine hydrochloride 100 mg. Amantadine is an antiviral drug that also has effects on the central nervous system. In Parkinson's disease, it is believed to work by increasing the release of dopamine and preventing its reuptake, in addition to its antagonistic effect at glutamate NMDA receptors, which may help relieve motor symptoms and dyskinesia caused by levodopa.
Stalipark Tablets Ingredients
Stalipark tablets contain a triple combination of active ingredients that work synergistically to treat the symptoms of Parkinson's disease, at specific concentrations:
Levodopa: 100 mg, a substance converted in the brain to dopamine, replenishing the deficiency of this important chemical.
Carbidopa: 25 mg, an inhibitor of the decarboxylase enzyme that converts levodopa to dopamine outside the brain. Carbidopa helps increase the amount of levodopa that reaches the brain and reduces peripheral side effects.
Entacapone: 200 mg, an inhibitor of the catechol-O-methyltransferase (COMT) enzyme, which breaks down levodopa in the brain. Entacapone helps prolong the effect of levodopa and reduce periods of motor "blockage."
Information about PK-Merz tablets
Drug category: Drugs for the treatment of Parkinson's disease
Drug classification: Anti-Parkinson's agent, antiviral
Pharmaceutical form: Tablets
Pharmaceutical family: Cyclic amine derivatives
Active ingredient: Amantadine hydrochloride (100 mg)
Information about Stalipark tablets
Drug category: Drugs for the treatment of Parkinson's disease
Drug classification: Combination of levodopa, carbidopa, and entacapone
Pharmaceutical form: Tablets
Pharmaceutical family: Anti-Parkinson's agents
Active ingredients: Levodopa (100 mg), carbidopa (25 mg), entacapone (200 mg)