Cardixin tablets are a valuable medication used to support heart function, particularly in patients with congestive heart failure and certain types of cardiac arrhythmias such as atrial fibrillation and atrial flutter. Its formula contains an active ingredient belonging to a group of drugs called digitalis glycosides, which have unique effects on the heart muscle and the electrical conduction system in the heart. Cardixin improves the heart's ability to pump blood more efficiently and controls the rate and regularity of the heartbeat. Due to the narrow therapeutic safety margin of digoxin, its use requires close medical supervision and strict adherence to the doctor's instructions.
The active ingredient in Cardixin tablets
Cardixin tablets contain the following active ingredient:
Digoxin: a natural glycoside extracted from the digitalis plant (Digitalis purpurea). Digoxin works by inhibiting the sodium-potassium (Na+/K+ ATPase) pump in cardiac muscle cells. This inhibition leads to an increase in the concentration of sodium ions within the cell, which in turn leads to an increase in the concentration of calcium ions. Increasing intracellular calcium enhances the force of myocardial contraction (a positive cardiotonic effect), improving the heart's ability to pump blood. In addition, digoxin affects the electrical conduction system in the heart, slowing the conduction of electrical impulses through the atrioventricular node (AV node), helping to control the rapid and irregular heartbeat associated with certain arrhythmias such as atrial fibrillation.
Available Strengths
Cardixin tablets are available in various strengths to facilitate dose adjustments for each patient based on their medical condition, weight, and response to treatment. Common strengths available on the market include:
0.125 mg
0.25 mg
Other strengths or dosage forms, such as oral solution or intravenous injection, may be available, but tablets are the most common form for regular use.
Indications for use of Cardixin tablets
Cardixin tablets are primarily used to treat the following conditions:
Congestive heart failure: Digoxin helps improve symptoms of heart failure by increasing the force of heart muscle contraction, which improves blood circulation and reduces symptoms such as shortness of breath and leg swelling. It is often used with other medications such as diuretics, angiotensin-converting enzyme (ACE) inhibitors, or angiotensin receptor blockers.
Some heart rhythm disorders:
Atrial fibrillation: Digoxin helps control the rapid and irregular ventricular heart rate associated with atrial fibrillation by slowing conduction through the atrioventricular node.
Atrial flutter: It can also be used to control the heart rate in cases of atrial flutter.